There’s a lot that’s nonetheless to be explored, with regard to the novel coronavirus that causes COVID-19. Because the healthcare sector in several international locations seems for solutions as to how the physique reacts and defends itself when the virus invades it, newer prospects emerge day by day. Amongst them is the issue of the guts, and the way it continues to operate within the presence of the viral an infection.
Individuals who have blood clots, virtually at all times expertise a cough and sharp ache within the chest. Clotting is without doubt one of the physique’s pure responses to harm, and it happens when a quantity of blood adjustments to a semi-solid state with a view to forestall extreme blood loss, says Dr Zakia Khan, Senior Interventional Heart specialist, Fortis Hospital, Kalyan.
“Emerging evidence indicates that COVID-19 leads to blood clots in an estimated 30 per cent of critically-ill patients. A blood clot (also called a thrombus), increases the risk of complications and death among those who have COVID-19. This infection causes blood clots in 20–30 per cent of critically ill patients.”
Dr Khan goes on to say that clots that type inside a deep vein may be extraordinarily harmful. These clots might not dissolve on their very own, they usually can cease the blood move. In some conditions, a clot can break off and journey to a different a part of the physique. “This thrombus is then called an ’embolus’. If the embolus reaches the brain, heart, or lungs, it can result in a life-threatening condition, such as a heart attack or stroke.”
The physician says that analysis suggests clotting happens when the novel coronavirus assaults the endothelial cells that line the blood vessels. “The virus does this by binding to the ACE2 receptors, which are present in the endothelial cell membrane. Once bound to the receptors, blood vessels release proteins that cause the blood to clot. Studies also indicate that COVID-19 causes the body’s immune system to trigger a hyperactive inflammatory response. This inflammation may also cause clotting. There are various other factors that may also play a role in blood clotting in people with COVID-19.”