Endometriosis is the main reason behind infertility in ladies, a indisputable fact that drives many to pursue in-vitro fertilisation (IVF). “Research has found that infertility affects around 30–50 percent of women with endometriosis. It is a fact that endometriotic women who have undergone IVF have a lesser success rate as compared to their peers who are undergoing IVF for other indications. But in many cases, they do successfully conceive, carry and deliver a healthy baby,” mentioned Dr Aswati Nair, fertility guide, Nova IVF.
Endometriosis begins proper from a younger age and as it’s a progressive illness. The indicators and signs hold worsening all through the ladies’s reproductive life. Moreover excruciating pelvic ache and infertility, different signs embody:
*Ache throughout intercourse
*Ache with ovulation
*Low again ache
*Painful bowel actions
*Constipation or diarrhea
The hyperlink between endometriosis and infertility
“According to a report published in 2017, endometriosis is a very common disease that occurs in 6 to 10 per cent of the general female population; in women with pain, infertility, or both, the frequency is 35–50 per cent. About 25 to 50 per cent of infertile women have endometriosis, and 30 to 50 per cent of women with endometriosis are infertile. However, the awareness of this condition in India is very low. Unfortunately, some women come to know about it when they experience difficulty getting pregnant. Various researches are still on to find the exact reason why women with endometriosis are infertile,” Dr Nair informed indianexpress.com.
Some unproven theories say:
Irritation causes the manufacturing of chemical compounds often called cytokines. These cytokines can inhibit the sperm and egg cells, making fertilisation harder.
Scarring and adhesions that happen with endometriosis can block the fallopian tubes or uterus, making it tough for the sperm to fulfill the egg.
Endometrial tissue on the ovaries can inhibit ovulation, stopping the discharge of an egg.
Is IVF therapy protected for endometriotic ladies?
“Yes, IVF treatment is definitely safe for endometriotic women. Some clinicians prefer to take out endometriotic cyst from the ovary prior to taking up for IVF, this could be the double edged sword because the ovarian reserve of the patient can go down after the surgery. Hence most clinicians go ahead with IVF and ICSI (Intracytoplasmic Sperm Injection) without removal of the endometriotic cyst,” she mentioned.
She added: “Even a 2011 study published in Human Reproduction used ultrasounds and questionnaires from women with endometriosis who received IVF to explore if the procedure had any effect on their disease. It concluded that IVF does not expose women to a consistent risk of endometriosis-related symptom progression. However, experts suggest that ultrasounds are not the best way to diagnose and track endometriosis. The progression needs to be determined via laparoscopy which in the present date is a gold standard form of investigation to diagnose endometriosis.”